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1

Nucleotides, Part LXIII, New 2-(4-Nitrophenyl)ethyl(Npe)- and 2-(4-Nitrophenyl)ethoxycarbonyl(Npeoc)-Protected 2′-Deoxyribonucleosides and Their 3′-Phosphoramidites – Versatile Building Blocks for Oligonucleotide Synthesis

Holger Lang, Margarete Gottlieb, Michael Schwarz, Silke Farkas, Bernd S. Schulz, Frank Himmelsbach, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

2

Nucleotides Part LXX : Inhibition of HIV-1 Replication by Chemically Synthesized, Nuclease-Resistant, Nontoxic (2′→5′)-Oligoadenylate Agonists

Ramamurthy Charubala, Wolfgang Pfleiderer, Robert J. Suhadolnik, Kathryn T. Iacono, Nicholas F. Muto, Joseph W. Homan, Camille Martinand-Mari, Susan E. Horvath, Earl E. Henderson, Amber Steele, Thomas

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 191 KB

english, 2002

3

Synthese von (±)-Predicentrin

Ramamurthy Charubala, Bantwal Ramachandra Pai, Tuticorin Raghavachari Govindachari, Narayana Viswanathan

Journal:

European Journal of Inorganic Chemistry

Year:

1968

File:

PDF, 193 KB

1968

4

ChemInform Abstract: Nucleosides. Part 62. Synthesis of 6-Methyl-8-(2-deoxy-β-D-ribofuranosyl)isoxanthopterin and Derivatives.

M. MELGUIZO, M. GOTTLIEB, R. CHARUBALA, W. PFLEIDERER

Journal:

Year:

1998

File:

PDF, 39 KB

1998

5

ChemInform Abstract: New Photolabile Protecting Groups in Nucleoside and Nucleotide Chemistry — Synthesis, Cleavage Mechanisms and Applications.

H. GIEGRICH, S. EISELE-BUEHLER, CH. HERMANN, E. KVASYAK, R. CHARUBALA, W. PFLEIDERER

Journal:

Year:

1999

File:

PDF, 29 KB

1999

6

ChemInform Abstract: Nucleotides. Part 63. New 2-(4-Nitrophenyl)ethyl(Npe)- and 2-(4-Nitrophenyl)ethoxycarbonyl(Npeoc)-Protected 2′-Deoxyribonucleosides and Their 3′-Phosphoramidites — Versatile Building Blocks for Oligonucleotide Synthesis.

Holger Lang, Margarete Gottlieb, Michael Schwarz, Silke Farkas, Bernd S. Schulz, Frank Himmelsbach, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Year:

2000

File:

PDF, 26 KB

2000

7

ChemInform Abstract: Nucleotides. Part 70. Inhibition of HIV-1 Replication by Chemically Synthesized, Nuclease-Resistant, Nontoxic (2′→5′)-Oligoadenylate Agonists.

Ramamurthy Charubala, et al. et al.

Journal:

Year:

2002

File:

PDF, 27 KB

2002

8

Notiz über das natürliche Auftreten von 3-Phenylisocumarin

Ramamurty Charubala, Armin Guggisberg, Manfred Hesse, Hans Schmid

Journal:

Helvetica Chimica Acta

Year:

1974

File:

PDF, 134 KB

1974

9

Umamidierungsreaktionen an cyclischen Amino-amid-Systemen. 3. Mitteilung über Umamidierungsreaktionen

Armin Guggisberg, Urs Kramer, Christian Heidelberger, Ramamurty Charubala, Euripides Stephanou, Manfred Hesse, Hans Schmid

Journal:

Helvetica Chimica Acta

Year:

1978

File:

PDF, 817 KB

1978

10

Nucleotide. IX. Synthese und Eigenschaften von 1-(2′-Desoxy-D-ribofuranosyl)-lumazin-3′-monophosphaten

Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1979

File:

PDF, 497 KB

1979

11

Nucleotide. X. Synthese und Eigenschaften von Dinucleosidmonophosphaten mit 2′-Desoxyadenosin und 1-(2′-Desoxy-β-D-ribofuranosyl)-lumazinen als Bausteine

Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1979

File:

PDF, 941 KB

1979

12

Nucleotide. XV. Synthese und Eigenschaften von 2′-O-t-Butyldimethylsilyl-5′-O-monomethoxytritylribonucleosid-3′-phosphotriestern, Ausgangssubstanzen für Oligonucleotid-Synthesen

Gunter Silber, Dieter Flockerzi, Rajendra Singh Varma, Ramamurthy Charubala, Eugen Uhlmann, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1981

File:

PDF, 753 KB

1981

13

Nucleotides. Part XXV. Chemical synthesis of the hexaribonucleotide C-A-A-C-C-A

Misuzu Lchiba, Ramamurthy Charubala, Rajendra S. Varma, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1986

Language:

english

File:

PDF, 638 KB

english, 1986

14

Nucleotides. Part XXVII Bis[2-(p-nitrophenyl)ethyl] Phosphorochloridate, a New Versatile Phosphorylating Agent in Nucleotide Chemistry

Frank Himmelsbach, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1987

Language:

english

File:

PDF, 628 KB

english, 1987

15

Nucleotides. Part XXVIII. Chemical syntheses of the 2′-5′-cordycepin-trimer core

Ramamurthy Charubala, Eugen Uhlmann, Frank Himmelsbach, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1987

Language:

english

File:

PDF, 844 KB

english, 1987

16

Nucleotides part XXX Chemical synthesis of adenylyl-(2′ → 5′)-adenylyl-(2′ → 5′)-8-azidoadenosine, and activation and photoaffinity labelling of RNase L by [32P]p5′A2′p5′A2′p5′N38A

Ramamurthy Charubala, Wolfgang Pfleiderer, Robert W. Sobol, Shi Wu Li, Robert J. Suhadolnik

Journal:

Helvetica Chimica Acta

Year:

1989

Language:

english

File:

PDF, 511 KB

english, 1989

17

Nucleotides. Part XXXI. Modified Oligomeric 2′–5′ A Analogues: Synthesis of 2′–5′ oligonucleotides with 9-(3′-azido-3′-deoxy-β-D-xylofuranosyl)adenine and 9-(3′-amino-3′-deoxy-β-D-xylofuranosyl)adenine as modified nucleosides

Piet Herdewijn, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1989

Language:

english

File:

PDF, 785 KB

english, 1989

18

Nucleotides. Part. XXXII. Synthesis of 2′–5′ Connected oligonucleotides. Prodrugs for antiviral and antitumoral nucleosides

Piet Herdewijn, Ramamurthy Charubala, Erik De Clercq, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1989

Language:

english

File:

PDF, 703 KB

english, 1989

19

Nucleotides. Part XXXV. Synthesis of 3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenyIyl-(2′–ω)-9-(ω-hydroxyalkyl)adenines

Sergey N. Mikhailov, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 293 KB

english, 1991

20

Nucleotides. Part XXXVIII.. Syntheses and characterization of phosphorothioate analogues of (2′–5′) adenylate dimer and trimer and their 5′-O-monophosphates

Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 551 KB

english, 1992

21

Nucleotides. Part XLV. Synthesis of new (2′–5′)adenylate trimers, containing 5′-amino-5′-deoxyadenosine residues at the 5′-end of the oligoadenylate chain, and of its analogues, carrying a 9-[(2-hydroxyethoxy)methyl]adenine residue at the 2′-terminus

Evgeny I. Kvasyuk, Tamara I. Kulak, Igor A. Mikhailopulo, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 607 KB

english, 1995

22

Nucleosides. Part LIX. The 2-(4-nitrophenyl)ethylsulfonyl (Npes) Group: A New Type of Protection in Nucleoside Chemistry

Magdalena Pfister, Helga Schirmeister, Marion Mohr, Silke Farkas, Klaus-Peter Stengele, Tilman Reiner, Martin Dunkel, Surendra Gokhale, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 2.71 MB

english, 1995

23

Nucleotides. Part LXXVI : Synthesis and Properties of New Isoalloxazine (=Benzo[g]pteridine-2,4(1H,3H)-dione) Derivatives as Labels for Oligonucleotides

Evgeny Kvassiouk, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Helvetica Chimica Acta

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

24

Nucleotide, XII. Synthese und Eigenschaften von Trinucleosiddiphosphaten mit Thymidin, 2′-Desoxyadenosin und 1-(2′-Desoxy-α- sowie 1-(2′-Desoxy-β-D-ribofuranosyl)lumazinen als Bausteine

Ramamurthy Charubala, Willi Bannwarth, Wolfgang Pfleiderer

Journal:

European Journal of Organic Chemistry

Year:

1980

File:

PDF, 832 KB

1980

25

Nucleoside, XXXVII. Synthese und Eigenschaften von 2′-O- und 3′-O-(tert-Butyldi-methylsilyl)-5′-O-(4-methoxytrityl)- sowie 2′,3′-Bis-O-(tert-butyl-dimethylsilyl)ribonucleosiden — Ausgangssubstanzen für Oligoribonucleotid-Synthesen

Dieter Flockerzi, Gunter Silber, Ramamurthy Charubala, Wilhelm Schlosser, Rajendra Singh Varma, Frank Creegan, Wolfgang Pfleiderer

Journal:

European Journal of Organic Chemistry

Year:

1981

Language:

german

File:

PDF, 1.11 MB

german, 1981

26

Nucleotide, XVI. Synthese und Eigenschaften von Adenylyl-adenylyl-adenosinen

Ramamurthy Charubala, Eugen Uhlmann, Wolfgang Pfleiderer

Journal:

European Journal of Organic Chemistry

Year:

1981

File:

PDF, 967 KB

1981

27

(2′-5′)Oligoadenylate and intracellular immunity against retrovirus infection

Heinz C. Schröder, Robert J. Suhadolnik, Wolfgang Pfleiderer, Ramamurthy Charubala, Werner E.G. Müller

Journal:

International Journal of Biochemistry

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

28

O(2),1,9-trimethyluric acid and 1,3,7,9-tetramethyluric acid in leaves of different Coffea species

Hans Wanner, Marcela Pešáková, Thomas W. Baumann, Ramamurty Charubala, Armin Guggisberg, Manfred Hesse, Hans Schmid

Journal:

Year:

1975

Language:

english

File:

PDF, 341 KB

english, 1975

29

The p-nitrophenylethyl (NPE) group: A versatile new blocking group for phosphate and aglycone protection in nucleosides and nucleotides

Frank Himmelsbach, Bernd S. Schulz, Thomas Trichtinger, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Year:

1984

Language:

english

File:

PDF, 1.67 MB

english, 1984

30

Synthesis and properties of 3′-deoxyadenylate trimer dA2′p5′A2′p5′A

Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 225 KB

english, 1980

31

A new solid phase approach for rapid syntheses of oligonucleotides bearing a 3′-terminal phosphate group

Eduard Felder, Robert Schwyzer, Ramamurthy Charubala, Wolfgang Pfleiderer, Bernd Schulz

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 259 KB

english, 1984

32

Synthesis of a modified 2′, 5′-Adenylate trimer with a 2′,3′-Di-O-(2-Carboxyethyl)-ethylidene terminal group

Evgeny I. Kvasyuk, Tamara I. Kulak, Galina T. Zaitseva, Igor A. Mikhailopulo, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 198 KB

english, 1984

33

Synthesis of a new 125I-labeled tyrosine methyl ester conjugate of adenylyl-(2′-5′)-adenylyl-(2′-5′)-[2′,3′-di-O-(2-carboxyethyl)ethylidene]adenosine

Evgeny I. Kvasyuk, Tamara I. Kulak, Svetlana M. Shulyakovskaya, Mikhail V. Makarenko, Igor A. Mikhailopulo, Charubala Ramamurthy, Wolfgang Pfleiderer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 217 KB

english, 1996

34

Studies on the syntheses of heterocyclic compounds—CDLXVII : Photolytic synthesis of kreysiginine-type compounds

T. Kametani, T. Kohno, R. Charubala, K. Fukumoto

Journal:

Year:

1972

Language:

english

File:

PDF, 358 KB

english, 1972

35

Synthesis of O6-p-nitrophenylethyl guanosine and 2′-deoxyguanosine derivatives

Thomas Trichtinger, Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 251 KB

english, 1983

36

Synthesis of inosinate trimer I2′p5′I2′pt′I and tetramer I2′p5′I2′p5′I2′p5′I

Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 419 KB

english, 1982

37

Synthesis and properties of adenylate trimers A2′p5′A2′p5′A, A2′p5′A3′p5′A and A3′p5′A2′p5′A

Ramamurthy Charubala, Wolfgang Pfleiderer

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 212 KB

english, 1980

38

Synthesis of new modified 2′,5′-adenylate trimers carrying 3′-amino-3′-deoxyadenosine at the 2′-terminus

Wolfgang Pfleiderer, Frank Himmelsbach, Ramamurthy Charubala

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 383 KB

english, 1994

39

The p-Nitrophenylethyl Group - An Universal Blocking Group in Nucleoside and Nucleotide Chemistry

Pfleiderer, W., Himmelsbach, F., Charubala, R., Schirmeister, H., Beiter, A., Schulz, B., Trichtinger, T.

Journal:

Nucleosides and Nucleotides

Year:

1985

Language:

english

File:

PDF, 424 KB

english, 1985

40

ChemInform Abstract: Chemical Synthesis of 2′,5′-Oligoadenylate Analogues

R. CHARUBALA, W. PFLEIDERER

Journal:

Year:

1995

File:

PDF, 24 KB

1995

41

ChemInform Abstract: Nucleotides. Part 45. Synthesis of New (2′→5′)Adenylate Trimers, Containing 5′-Amino-5′-deoxyadenosine Residues at the 5′-End of the Oligoadenylate Chain, and of Its Analogues, Carrying a 9-((2- Hydroxyethoxy)methyl)adenine Residue at the 2′-Terminus.

E. I. KVASYUK, T. I. KULAK, I. A. MIKHAILOPULO, R. CHARUBALA, W. PFLEIDERER

Journal:

Year:

1996

File:

PDF, 28 KB

1996

42

ChemInform Abstract: Nucleosides. Part 59. The 2-(4-Nitrophenyl)ethylsulfonyl (Npes) Group: A New Type of Protection in Nucleoside Chemistry.

M. PFISTER, H. SCHIRMEISTER, M. MOHR, S. FARKAS, K.-P. STENGELE, T. REINER, M. DUNKEL, S. GOKHALE, R. CHARUBALA, W. PFLEIDERER

Journal:

Year:

1996

File:

PDF, 27 KB

1996

43

Inhibition of DNA topoisomerase I activity by 2′,5′-oligoadenylates and mismatched double-stranded RNA in uninfected and HIV-1-infected H9 cells

Heinz C. Schröder, Merike Kelve, Heike Schäcke, Wolfgang Pfleiderer, Ramamurthy Charubala, Robert J. Suhadolnik, Werner E.G. Müller

Journal:

Chemico-Biological Interactions

Year:

1994

Language:

english

File:

PDF, 1.20 MB

english, 1994

44

A route to 2′,5′-oligoadenylates with increased stability towards phosphodiesterases

A.V. Itkes, M.Ya. Karpeisky, O.N. Kartasheva, S.N. Mikhailov, G.P. Moiseyev, W. Pfleiderer, R. Charubala, G.I. Yakovlev

Journal:

Year:

1988

Language:

english

File:

PDF, 322 KB

english, 1988

45

2′,5′-phosphodiesterase activity depends upon the presence of a 3′-hydroxyl moiety in the penultimate position of the oligonucleotide substrate

David Alster, Danuta Brozda, Yukio Kitade, Alice Wong, Ramamurthy Charubala, Wolfgang Pfleiderer, Paul F. Torrence

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 275 KB

english, 1986

46

Inhibition of Epstein-Barr virus-associated nuclear antigen (EBNA) induction by (2′,5′)oligoadenylate and the cordycepin analog: Mechanism of action for inhibition of EBV-induced transformation

Earl E. Henderson, Paul W. Doetsch, Ramamurthy Charubala, Wolfgang Pfleiderer, Robert J. Suhadolnik

Journal:

Year:

1982

Language:

english

File:

PDF, 337 KB

english, 1982

47

Chemical Synthesis and Biological Activity of 2′-5′-Phosphorothioate Tetramer Cores

Charubala, R., Pfleiderer, W., Suhadolnik, R. J., Sobol, R. W.

Journal:

Nucleosides and Nucleotides

Year:

1991

Language:

english

File:

PDF, 229 KB

english, 1991

48

Phosphorothioate analogs of (2'-5')(A)4: agonist and antagonist activities in intact cells

Charachon, Guillaume, Sobol, Robert W., Bisbal, Catherine, Salehzada, Tamim, Silhol, Michele, Charubala, Ramamurthy, Pfleiderer, Wolfgang, Lebleu, Bernard, Suhadolnik, Robert J.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.58 MB

english, 1990

49

HIV-1 reverse transcriptase: Inhibition by 2',5'-oligoadenylates

Sobol, Robert W., Fisher, William L., Reichenbach, Nancy L., Kumar, Amalendra, Beard, William A., Wilson, Samuel H., Charubala, Ramamurthy, Pfleiderer, Wolfgang, Suhadolnik, Robert J.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.32 MB

english, 1993

50

Phosphorothioate Analogs of 2–5A: Elucidation of the Stereochemical Course of the Enzymes of the 2–5A Synthetase/RNase L System

Karikó, Katalin, Li, Shu Wu, Sobol, Robert W., Suhadolnik, Lorraine, Reichenbach, Nancy L., Suhadolnik, Robert J., Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 503 KB

english, 1987

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